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Wiest, J.: Chemisch definiert – ein zellbasierter Zytotoxizitätsassay ohne fötales Kälberserum. Biospektrum (2017) 23: 61. doi:10.1007/s12268-017-0768-6

Tests for cytotoxicity – respectively biocompatibility – are performed e.g.
for biological evaluation of medical devices or during the development of
microphysiometric systems. Here, often cell culture methods which
involve the use of fetal bovine serum (FBS) are employed. However, using
FBS raises scientific and ethical concerns. In the presented work a pro
tocol for a chemically defined test for cytotoxicity is described.
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