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Wiest, J.: Chemisch definiert – ein zellbasierter Zytotoxizitätsassay ohne fötales Kälberserum. Biospektrum (2017) 23: 61. doi:10.1007/s12268-017-0768-6

Tests for cytotoxicity – respectively biocompatibility – are performed e.g. for biological evaluation of medical devices or during the development of microphysiometric systems. Here, often cell culture methods which involve the use of fetal bovine serum (FBS) are employed. However, using FBS raises scientific and ethical concerns. In the presented work a protocol for a chemically defined test for cytotoxicity is described.
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