BIOCHIP-H AND CONTACT-SET

Our new Biochip-H and a simple contact-set are available


BioChip-H:
Improved multiparametric BioChip (pH, pO2, Impedance, MEA, Stimulation-electrodes and temperature) for measurement of cellular vitality and changes in bioimpedance on glass substrate for optical access via microscope.

EMBC’13

Meet us at the “35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society“.


cellasys will contribute with an invited talk “Label-Free Monitoring of Whole Cell Vitality” and a poster entitled “Evaluation of an Inkjet Printed Biochip”.

Label-Free Monitoring of Whole Cell Vitality
The Intelligent Mobile Lab (IMOLA) delivers metabolic and morphological parameters of living cells in a label-free and real time way. It represents a key technology for the development of new cell-based assays. Electrochemical microsensors are used to measure the extracellular acidification (pH), cellular respiration (pO2), changes in cell number and morphology (electric impedance) in a controlled environment. These parameters are closely linked to the intracellular signaling network of the living cells. They are thus likely to respond sensitively to changes in cellular vitality. A wide spectrum of cell types can be tested with the system, including adherent and suspended cells, continuous cell lines, primary cells or tissue samples. The platform is described in detail and applications in the field’s oncology, toxicology and environmental monitoring are shown.

Evaluation of an Inkjet Printed Biochip
Micro-sensor biochips have various applications in the field of live sciences. In this work, we present first results from a biochip manufactured in inkjet technology. The micro-sensor, contacts and conductors of this biochip were printed with an inkjet process onto a flexible Kapton substrate. The micro-sensor is an interdigitated electrode structure comprising of a mixture of carbon nanoparticles and multi-walled carbon nanotubes. In our project the reaction of the structure toward changes in pH, dissolved oxygen concentration, glucose and lactate was evaluated.

ACHEM ASIA 2013

cellasys will be represented by the Assosiation of German Biotechnology Companies at the AchemAsia 2013.


Please click here for more information

POTSDAM DAYS ON BIOANALYSIS 2012

Meet us at the Potsdam Days on Bioanalysis 2012.


During the the Potsdam Days on Bioanalysis 2012 Dr. Joachim Wiest will give a talk entitled “Label-free monitoring of living cells”.

LABEL-FREE TECHNOLOGIES

Meet us at the Elsevier – Label-Free Technologies – Advances and Applications conference in Amsterdam.


During the Elsevier – Label-Free Technologies – Advances and Applications conference in Amsterdam from 1st to 3rd of November 2012 we will show a presentation on “Biochip-based electrochemical platform for label-free monitoring of living cell”

17th EUROPEAN CONGERSS ON ALTERNATIVES TO ANIMAL TESTING

Meet us at the 17th European Congress on Alternatives to Animal Testing


Dr. Joachim Wiest will give a talk entiteled “BioChip-based electrochemical platform for the label-free monitoring of living cells” at the 17th European Congress on Alternatives to Animal Testing.

EMBC 2012

cellasys presents a Minisymposium on “Monitoring of living cells” at the 34th Annual International Conference of the IEEE Engineering in Medicine & Biology Society. Speakers include Dr. Martin Brischwein, Dr. Johannes Clauss and Dr. Martin Koch.


EMBC 2012 Minisymposium “Monitoring of Living Cells” in Room Sapphire 410 on Friday 31th August 2012 from 16:30 h until 17:30 h:

I) Martin Brischwein (TU Munich, Germany): Label-Free, Sensor-Based Cell Assays: State of the Art

Cell based assays provide information to the chemical, pharmaceutical, food industries and to physicians for diagnostic and therapeutical decisions. While such assays are typically bound to the use of (optical) markers, label-free assays working with microsensor techniques have emerged.

II) Joachim Wiest (cellasys GmbH, Germany): Electrochemical Technology and Methods for Data Processing for Label Free Monitoring of Living Cells

The presented work describes various microsensor technologies which are suitable for online, marker-free, multi-parametric monitoring of living cells. Furthermore different aspects of data processing, interpretation and correlation are discussed.

III) Johannes Clauss (TU Munich, Germany): Label Free Cellular Monitoring: From in Vitro to in Vivo

Label-free monitoring technologies for biological and chemical analysis are fast growing. For in vivo analysis these label-free techniques are even more crucial than for in vitro measurement. A wireless implant system including an amperometric oxygen sensor for the human body was developed, which can be implanted next to a tumor. The sensor system is capable of continuously monitoring tissue in vivo under real-time conditions over a long period of time.

IV) Martin Koch (Feldkraft Ltd., Denmark): Manipulation of Living Cells by Employing Dynamic Fields

Living cells can be swayed by dynamic fields via magnetic nanoparticles. A hereto related procedure is the well known therapy called hyperthermia. In these treatments electromagnetic fields in our case however magnetic fields are applied.

PRESENTATION AT THE BIOSENSOR 2012

At the Biosensor 2012 in Cancun / Mexico recent applications of the IMOLA-IVD technology in combination with 3D microtissue will be presented.


The presentation is entitled: “Online monitoring of 3D hepatic microtissue using electrochemical microsensors”

BIOCHIP DATASHEET AVAILABLE

Datasheet of BioChip-C and BioChip-G in downloadsection


cellasys GmbH, a spin-out of Technische Universität München published detailed description of their micro-sensor-chips for investigation of living cells. For the first time, now the pin configuration is available to the public. Before the upcoming analytica in April 2012 the high-tech company posted the datasheet on www.cellasys.com to allow customers to use the BioChips independent of the proprietary IMOLA-IVD technology. Dr. Joachim Wiest, CEO of cellasys states: „With opening the interface description we welcome new partners to integrate our BioChips into their own devices.“ Joint developments with a partner for live cell imaging are already ongoing.

ONLINE MONITORING OF 3D HEPATIC MICROTISSUE …

… using electrochemical microsensors.


Presentation at the 3D Cell Culture 2012.

At the 3D Cell Culture 2012 from 14.03.2012 – 16.03.2012 in Zurich/Switzerland recent applications of the IMOLA-IVD technology in combination with 3D microtissue will be presented.